North Carolina State University
Dr. Hyman is a Professor of Microbiology at NC State University and has 30 years’ experience in the characterization of microbial degradation processes. His research focuses on the cometabolic biodegradation of ethers and chlorinated hydrocarbons by aerobic hydrocarbon-oxidizing bacteria and fungi. His laboratory uses physiological, genome-enabled proteomic, and stable-isotope-based approaches to characterize the enzymes, pathways, intermediates and physiological consequences of microbial co-metabolism
Bacterial Cometabolism of 1,4-Dioxane: “Omic” insights and Practical Applications
This presentation will describe recent “omic” insights into the enzymes that enable gaseous hydrocarbon-oxidizing bacteria to cometabolically degrade environmentally relevant (≤100 µg/L) concentrations of 1,4-dioxane and associated chlorinated co-contaminants. The presentation will summarize recent findings from genome-enabled proteomic analyses and activity-based labeling studies and will illustrate how these findings are relevant to existing and novel emerging approaches for the cometabolic degradation of 1,4-dioxane.